What is mometasone furoate monohydrate used for?
What is mometasone furoate monohydrate used for?
Mometasone nasal spray is used to prevent and relieve symptoms of sneezing, runny, stuffy, or itchy nose caused by hay fever or other allergies. It is also used to treat nasal polyps (swelling of the lining of the nose).
What are the side effects of mometasone furoate nasal spray?
Side Effects
- Bloody mucus or unexplained nosebleeds.
- cold.
- hoarseness.
- increased abdominal or stomach pain and cramping during menstrual periods.
- muscle or bone pain.
- stuffy or runny nose.
Is mometasone nasal spray a steroid?
About mometasone nasal spray Mometasone is also used to treat other conditions, such as nasal polyps in adults. Mometasone is a type of medicine known as a steroid (or corticosteroid). Corticosteroids are a copy of a hormone that your body makes naturally.
Does mometasone furoate lighten skin?
Results: Eighteen subjects completed the study. Most of the subjects in both groups got improvement at 1-25% repigmentation (50% in 0.1% tacrolimus group and 34% in 0.1% mometasone furoate group).
Is mometasone good for sinusitis?
Mometasone (Nasonex) is currently the only nasal steroid indicated for the treatment of acute sinusitis. It reduces the number of basophils and eosinophils in the mucosa and inhibits the late-phase reaction after exposure to allergens.
Is mometasone the same as Flonase?
Are Flonase and Nasonex the Same Thing? Flonase (fluticasone nasal spray) and Nasonex (mometasone furoate monohydrate) are corticosteroid nasal sprays used to treat nasal symptoms such as congestion, sneezing, and runny nose caused by seasonal or year-round allergies.
What is the structure of mometasone furoate?
Mometasone furoate is a 2-furoate ester, a steroid ester, an 11beta-hydroxy steroid, a 20-oxo steroid, an organochlorine compound and a 3-oxo-Delta (1),Delta (4)-steroid. It has a role as an anti-inflammatory drug and an anti-allergic agent. It derives from a mometasone.
What is the mechanism of action of mometasone?
Upon administration, mometasone binds to cytoplasmic GRs and subsequently activates GR-mediated gene expression. This results in the synthesis of certain anti-inflammatory proteins, while inhibiting the synthesis of certain inflammatory mediators.
What is the difference between mometasone and dexamethasone?
Mometasone is a synthetic corticosteroid with an affinity for glucocorticoid receptors 22 times higher than that of [ dexamethasone ]. Mometasone furoate also has a lower affinity to mineralocorticoid receptors than natural corticosteroids, making it more selective in its action.